(1) How much do you care about whom? In particular, do you care equally about everyone, or are you a jerk?
(2) How do you weight the relative value of things like money, health, longevity, entertainment?
(3) At what rate does the marginal utility of such things diminish?
Okay maybe that's a lot of wiggle room. Still, under any reasonable set of weights, making millions of people sick is not worth the money 3M made.
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