If you wanted to go a bit fancier you could get an RDX drive https://www.overlandtandberg.com/products/rdx-removable-stor... and some cartridges, but you're looking at $100-200 for the drive, plus the cartridges are more expensive than USB: https://www.rdxworks.com/Tandberg-Data-RDX-2TB-8789-RDX.aspx (A 5TB cartridge is $560, you could buy five USB drives and make five copies and that would likely be more reliable than one backup cartridge unless you were really unlucky).
They're designed for backup and archival and just appear as a USB drive. I'd go that way for business or if you're cycling cartridges a lot.
And out of your data, you can designate "Very important" things like tax returns, documents, etc (which is probably a small portion of the total) and burn those to CD or DVD as additional security.