Most experiments in science rely on correlation in controlled environment. To prove something entirely true you'd have to control all variables in the universe. As for theoretical science well a lot of it is just a choice of faith. Just listened to Wolfram in his first interview with Lex Fridman, like he said some things about evolution we'll never be able to prove. He also said evolution is kind of a religion itself which I'd agree with. If you can 100% invalidate some religion why should it change? What's the purpose for it to exist - to satisfy some spiritual need like any other material need? The pupose of church was to hold the truth in it's absolute form. If that's not the case you're merely a support group, a social club/community.