* The safety is massively different than fission because there is no 'run away' reaction. If you turn off the power, fusion will stop. Fission will keep going once started, and can be very dangerous if the cooling system fails.
* I do believe the fusion paths Helios is using emit neutrons, which is a big safety concern. Not only is neutron radiation directly deadly to humans, it's also a challenge to maintain containment. Neutrons are not magnetic, so matter must be used as a shield. Most materials that absorb a neutron will itself become radioactive. I'm unsure about the number of neutrons Helios is emitting, or will emit as they scale up.