Also the fact that it is structurally almost impossible for a layperson to give informed consent on a dangerous, highly experimental, early stage medical procedure, let alone a elective, non-medically necessary procedure. We have rules about human clinical testing for literally that reason.
They do not know the percent chance of death during early experimentation. They literally do not understand the procedure well enough to estimate the effects with sufficient confidence for it to be acceptable to do in human subjects. That is why it is called early stage and why we have animal testing, to establish these parameters as best we can for it to be acceptable to attempt on humans. This is literally the blood the human clinical testing rules around consenting to procedures is written in.
As someone who literally would have never existed albeit for human experimentation, I have something of an opinion that sometimes pushing the boundaries of science is worth ethical sausage making.