https://www.latimes.com/science/sciencenow/la-xpm-2013-sep-1...
Usually what I do is set it on recirculate, and then every ~10 minutes I periodically "flush" the CO2-laden interior air for a minute or so. Ideally, I'm able to do this "flush" when I'm away from a major city or high-traffic road (and not when driving behind a soot-spewing diesel bus/semi/garbage/cement truck).
I wish there were some way to automate this logic!
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(and yes, my dear observant reader, if I could recirculate "only" 90% of the exterior air it would achieve the same steady-state result, but modern cars got rid of the "slider" that lets you select a percentage of recirculate air... ::sigh::)