Why not regulate the genetic manipulation and bioengineering? It seems almost irrelevant whether it's an AI who's doing the work, since the physical risks would generally exist regardless of whether a human or AI is conducting the research. And in fact, in some contexts, you could even make the argument that it's safer in the hands of an AI (e.g., I'd rather Gain of Function research be performed by robotic AI on an asteroid rather than in a lab in Wuhan run by employees who are vulnerable to human error).