A lot of the research is entirely unnecessary. We know cadmium is biologically unnecessary. While it is important to quantify safe doses to understand the impact of pollution, getting the precise LD50 of it across various species does little to improve health outcomes.
We already know that dosages above 10 micrograms/kg of body weight is carcinogenic and should be avoided, so establishing where in the 100,000-300,000 microgram/kg range the LD50 resides does nothing for us.