I think what Blade Runner 2049 got wrong was the way they depicted having sex with the Joi instance. I assume in 2049 we'll either have Neuralink available to enter a virtual world (à la VRChat) where we can do it more realistically, or we'll have the ability to buy full sexbots and put the Joi instance in them.

We'll likely also have virutal brothels using AI along the same lines.