Agreed on compliance part – of course, in many cases (not in all though) PII must not be in dev/test envs.
Although, cannot agree with the former part. If your tests are running 2 days on a full size clone, and it's an OLTP case, what about users, do they suffer from long query duration too? It sounds like it's time to optimize queries and/or redesign test sets (or both).
If it's bad in testing, it will be bad in prod. That's the idea of testing.
Example: how do you check schema changes?