Not that I saw. I was in computer science. I knew people in education, business, math, physics, etc.

The reason my semester was hard was due to a poor professor and taking advanced classes as a freshman (several 300 levels, including math, which I struggle with).

I do know doctors in residency and others that have rough schedules, but that's not undergrad.

As an MIS undergrad student I had "that 1 semester" where I would work myself delirious. It was not a good time. However that was followed by 3 years of taking the minimum number of hours per semester to maintain scholarship and carefully selected schedules that never again required me to be in a classroom before 2pm. At first, I was actually surprised by how much faster it was to do schoolwork when not crushed under sleep debt. It turned out only having scheduled classes when I was actually awake made things a lot easier.