If I'm by myself on a plane, I REALLY do not want to talk to my row mates. Getting sat with someone chatty is my nightmare. It's nothing personal. It's just that it's the very rare occasion I am not flying with my young kids and I am relishing the opportunity to play a video game or watch a movie or read without anyone bugging me :)
The first time I had to travel for work after having kids was maybe the first time I'd actually enjoyed flying since pre-9/11. My point here isn't to crap on my kids, I love them dearly. But boy do they adjust your perception of everything.