Yes and no. There are absolutely baseline random factors that have a big impact on your life. You could genetic predisposition to something unpleasant, be born into Money, have a skin tone that’s discriminated against, have birth citizenship in a nation with a great social safety net. Lots of factors that can go either way.
We underestimate the importance of positive factors and overestimate the importance of negative factors. I think the best approach to dealing with this is:
1) practice Gratitude for the foundational positives
2) accept the foundational negatives
3) Embrace your sphere of control and deliberately choose compounding actions that build on the strengths and mitigate the weaknesses to improve your life.