Plain js on the frontend. Complex logic handled in rust-wasm. Backed handled in Rust using the Actix Web http server, using websockets, proxied through a very basic nginx instance with TLS.

My own servers for the entire cloud, maybe with CloudFlare as a CDN.

Avoid anything else as much as possible. If you need AI/ML, you're going to have to pull in some difficult extra stuff, so make sure the value is there.

Owing both to the unreasonableness of the modern javascript stack (node/eslint/jest/react/typescript/webpack) and also to the considerable improvement of vanilla js over the past 10 years, I really don't feel like all the extra frameworks are worth the overhead and dependency risk on the frontend. Vanilla js is really good these days! And when you need a boost, rust wasm is also really good.

I've found that it's a lot faster - and also a lot safer! - to build in vanilla js than I ever would have expected. Typescript still adds value, but imo not nearly enough value to earn a place in the stack.