I tried MS Flight Simulator with a Quest tethered to my desktop and I couldn't get the resolution high enough to be usable for the instrument panel. I'd have to still zoom in for them to be readable. The concept is amazing but I couldn't get reality to match up with it.
It was also weird not being able to see the my throttle and yoke and all the different buttons I needed to use. I didn't have enough hours on the setup to have it all be via muscle memory yet so I needed to be able to look at my cheat sheet sometimes.