I think one strong argument against this is SBF/FTX was highly funded by sophisticated investors and VCs. If they didn't catch it, why should anyone else? People believed FTX was making money through tx fees and front-running via Alameda. The classic "due diligence was done by others" scenario.
Saying this, people were skeptical of SBF in EA, worried about so many eggs in one basket, and didn't like crypto as a source of funding. It's a large group with many views!
I agree with double- and triple-checking all the math about risk and effectiveness. I'm interested in donating to effective charities that use my dollar in the best way and if you correctly find better ones to do so I'd donate :)