My only problem with Noita is that the back half of the game basically disregards most of the physics and chemistry systems. It’s more based around exploiting the build-a-wand system so you can e.g. generate infinite black hole chainsaw spells that let you blast through rock at a million miles an hour.

It is the only game I am aware of that I would say has a true “chemistry engine” along side its physics engine. (Though props to designers of Zelda BotW for giving objects internal properties besides just velocity & mass that facilitate reactions and interactions. Falling sand games that Noita takes a lot of inspiration also often have “chemistry” interactions but generally don’t incorporate physics bodies and are more of a simulation toy box than a game).