> On the other hand I have seen WP and CodeIgniter setups that even with 5 copies running on the largest AWS instances available, "optimized" to the hilt, caching everywhere possible, etc. absolute crumble under the load of 3k req per min. (not sec ... min).
This sounds like some other architectural problems - running nowhere near the largest instances available that was single node performance on EC2 in the 2000s.
There are concerns switching from local to SAN storage, of course, but that’s also shifting the problem if you care about durability.