I'm not saying it is entirely impossible. However, rotating volume data (which voxels are)
is computationally a lot more intensive. With polygonal objects you can just change the transformation matrix and re-render the screen and you're done. At most, you have to deform the vertices that make up the outer shell of the object to do things like make a person walk.
With voxels, you'd have to recompute all the voxels of the object on a 3d grid. Also there are issues with ragged boundaries, which can be prevented by using antialiasing, but which is probably trickier (=more computationally intensive) than in 2D...