Where "local truck" is "a vehicle that can fit at the location, unlike a semi" and "depot" is "nearby, where their semi is parked", sure. And they do frequently hire local help, rather than cart them across hundreds or thousands of miles.
But it's not like they're going to post office / Amazon / etc "hubs" and changing vehicles along the way - the human labor cost and increased risk would be far too high, though pods might be feasible. The same semi and the same driver does 99% of the distance, and often hires their own helpers. The local shuttling and helpers are entirely reasonable and often unavoidable.