Had the new world contain diseases and plagues for which old worlders had not developed resistance to or ways of dealing with then there might have been a completely different outcome. As plagues would have traveled back across the Atlantic resulting in Black plague levels of death.
You get the point, though. And we don't know what they could do regarding diseases or other nasty stuff...
* Cotton clothing - superior to Wool and Flax clothing that was hot, scratchy
* Clean cities - European streets had sewage flowing in the gutters. They were shocked at well developed urban centers with no public sewage issues
* Canoes - Lighter, faster, and more agile than European wooden boats
* Advanced Agriculture - They invented tomatoes, corn, potatoes and many more varieties that quickly became staple food in Europe (Polenta, Pizza, etc in Italy) and Africa (sweet potatoes)
Populations have been chronically under estimated. Various civilizations (Inca, Maya, etc) probably millions of people each, which then had a 95% die off rate when exposed for the first time to European diseases. These spread virally across civilizations to areas where no Europeans had yet visited.
Book was written in 2006, so I don't know what the current state of our understanding of the Americas history is.