I reversed the numeric row of my keyboard layout so that the symbols are typed without the shift key and the numerals use the shift key. With that arrangement, a number pad is important for any meaningful numeric input.

But as a programmer, I can't stress enough how valuable it is to type symbols without constantly reaching for the shift key. "Programmer Dvorak" does this as well, but then you have to learn a new arrangement of symbols and deal with numerals that aren't in numerical order.