This is also something I have been battling with in the past. All the cross GUI platforms have their quirks and problems and varying OS dependencies you are then married to. Since this is my own personal project, I decided cut the knot differently and just do the GUI parts native.

So far, I have found it be incredibly liberating. Instead of trying to instinctively shoe-horn functionality into something that will fit on all platforms, the code itself becomes much clearer when all the really "abstract" or "logic" code is completely separate from the platform code.

This is of course best practice anyway, but the decision to split this way made separation incredibly obvious. When the "logic" parts code cannot communicate with OS resources, you aren't tempted to put stuff where it doesn't belong.