I assume because you literally spend most of your life there, and if it doesn't mean something, that is ... awful?
I mean, there have been times / places in history where you work so that you have enough money to not die; and you enjoy your life with whatever pittance is left afterward.
I doubt anyone reading this website is in such a time or place.
Basically every corporation you can work for will have you doing something meaningless (and is dedicated to a meaningless pursuit besides). As the world population shrinks in the deep future, perhaps that will change - but right now it definitely will not.
As such, I have trouble seeing why you'd think any work you do means anything. Most likely it doesn't and that's okay. It is not within your control to have meaningful work available. It is within your control to have a healthier attitude towards your workplace and your work.
If you find your work to be meaningless, who am I to argue. But I've had a number of jobs at different companies at various places along the 'meaning' gradient. It's not all the same. Though I also agree that meaning is, to large degree, yours to make, at least as much as it is a property of the situation.