In my own experience the more I satiated my hedonistic desires the more I wanted and the less pleasure I attained from doing so. Furthermore it promoted a sense of selfishness in me that made the experience of living less fulfilling. Couple that with my own observations working in a variety of medical settings encountering a wide range of people from all walks of life. Without exception I noticed that the people who were selfish were unhappy and the people who were the most selfish were the most unhappy (correlation not causation I know but pertinent none the less). Generally the people who were most concerned about others well-being were gifted with a light and pleasant demeanour that gave me the strong impression that they were experiencing life in an altogether different (and to my eye more desirable) way than those that were selfish.

And the pattern running through all of that was that selfish people were always unhappy with what they had or what they were given, invariably showed little or no appreciation for anything. Selfless people were always appreciative of everything and anything.

The above is anecdotal but from my prospective not inconsequential. And for me at least, intentionally practising appreciation, when I manage to do so, never fails to have a positive impact on how I feel in the world. Just my two cents.