Even if the wildest dreams of transhumanists come true, that would not be the permanent abolition of death, merely postponing the inevitable. With every passing millennia, the odds of dying by accident or homicide would only grow. Even supposing mind uploading works - that strategy might keep you safe from accidents, but eventually you’ll die in the heat death of the universe. Schemes proposed to beat that are so extremely speculative-they are no more believable than religious afterlife claims (maybe even less so). Entropy always wins in the end-with the possible exception of unimaginably long timescales-eventually, maybe, we’ll all be resurrected as Boltzmann brains, or endure this exact life repeating an infinite number of times without change (Nietzsche, meet Poincaré). But odds are you’ll die long before that. Or our simulators will get bored with us, and turn this universe off.