No it's cheaper to just get a utility trailer and hook it to your existing vehicle. Even a compact economy car can do just fine towing one. They can carry up to 1500lbs for the smaller ones, and cost less than $1000. You don't have to pay the same road tax every year, or insurance. You don't have maintenance to do on it other than tires and wheel bearings which are all generic and dirt cheap.
I've been able to do all my house projects for the last 7-8 years towing one behind my Honda Fit. I've picked up motorcycles with it (which is way easier to load than a tall pickup bed). Picked up engines, car parts. I have hauled sheetrock, pavers, plywood, lumber, furniture... I have done countless dump runs... I have moved with it, and helped others move with it. The car + trailer ends up embarrassing the pickups who show up to help move, as they can't carry as much stuff as the car + trailer combo.
And when I'm not hauling things, the car seats 4 comfortably, and we can put stuff in the hatch without worrying about it getting wet... I get mid-30s mpgs.
Anything that's too big or heavy for my trailer... well I have it delivered. Chances are, that load is also too big for your average 1500 pickup.