It is frightening for patients who are already on vancomycin, and makes it harder for new patients to try it. The AASLD wants to see randomized controlled trial data; there have in fact already been two small such trials, but obviously not enough to satisfy them. I do think a better trial could be designed, and I'm actually trying to do that now. Finding the funding is a challenge because vancomycin is a generic drug. There are entities who would be willing to carry out such a trial if funds can be found.