Yeah, just not according to science.

E.g. there's ghrelin, cholecystokinin and other "satiety signals".

Except if you mean "satiefy is a mental construct" the same way pain is a mental construct. In which case, in a Kantian way, everything is, including space and time.

>What your brain tells you to put in your stomach is almost entirely divorced from nutritional requirements for thriving and surviving.

(a) You'd be surprised.

(b) It only appears that way because we have diverged in a exteremely small span of time (evolutionary speaking) into completely different circumstances and food availability.

Otherwise, what the brain tells us is very much based on nutritional requirements for thriving and surviving.

It's just that in 2022 we have an endless supply of food we can just order or walk into a supermarket and buy, as opposed to food scarcity where we don't know if we will be able to find something to hunt tomorrow - like the last 100,000 of thousands of years before historical times (and millions of years considering our primate ancestors)...