Quoting wikipedia (
https://en.wikipedia.org/wiki/Monkeypox#Causes)
Most human cases of monkeypox are acquired from an infected animal, though the route of transmission remains unknown. The virus is thought to enter the body through broken skin, the respiratory tract, or the mucous membranes of the eyes, nose, or mouth. Once a human is infected, transmission to other humans is common, with family members and hospital staff at particularly high risk of infection.