Part of what really tipped me off was my energy before and after the gym was much lower than it used to be. Also I would be tired starting around 2 PM in the afternoon, this isn't sleep related as I sleep like a baby, which I am grateful for. Also I never drank coffee or took lots of caffeine so I was perplexed as to why I would just crater in the afternoons.
After starting the treatment I am no longer tired in the afternoons, my mind feels sharper and I can tell I am recalling processing info better. The energy at the gym has improved as well.