Maybe there's some fundamental reason that specific approach won't work, but when we consider the massive improvements in DNA sequencing and analytical chemistry and nanotech over the past century, seems like we should have very little confidence that proteins will remain unreadable for the indefinite future. (Whereas things like integer factoring seem a lot more robust...)
I can fully see them trying to add something like this to a DVD so you couldn’t watch it more than X times or as a built in self destruct if someone tried to do a 100% bit-rip of the disk.
If they could come up with one that reacts with air or light then “right to repair” isn’t even an option.
You just need to think bigger and there’s unlimited options to protect IP from people who would misuse it for things like that pesky freedom they go on and on about.