This may be technically true, but since I don't want to spend a lot of time messing with command line tools then it might as well not be.
Edit - To add a little context since that on reflection seems too dismissive...
I did try a whole bunch of things a while back, include several variations on xrandr stuff. I never did get to a place where all the following were true:
Both screens were operating at their maximum resolution
All app windows were appropriately sized (readable fonts, correctly scaled menu bars, etc.)
Neither screen was blurry due to scaling
I wouldn't swear it was impossible but with recent versions of Ubuntu under Wayland I could have all three without having to do anything at the command line.
I love the command line. I just don't find messing around with config to make the basic system stuff work properly edifying.