One thing to consider is if you would have One API and a few knobs to control the experience and not have to worry about the underlying protocol-, reliability-, latency- aspects to build that experience. (particularly not worry about the shenanigans around tuning RTMP, RTP, HLS, or webrtc)
There are some use-cases in every industry.
* Finance/Company: earnings calls as mentioned before, all-hands meetings at companies (with several people queuing for questions and answers)
* Live Events (music or talkshows)
* Tutoring or education in general.
* Healthcare and education -- Surgeries which are broadcast to several schools and have active collaboration from some doctors. The large-scale interaction can begin much earlier before the surgery.