I'll also add that his comment about winning/losing is a bit off as well.
This isn't a competitive game, it's a cooperative one. Everyone needs to shake an odd number of hands. The game is won, when everyone in the room has shaken an odd number of hands. It's more a puzzle than a game.
There may be additional rules on if disconnected sub graphs are allowed or not, so with an even number of people, the puzzle is trivial to solve.