I’m not pushing 4K though, so mileage may vary. I’ve got a 27” TB2 Apple Cinema Display via TB2 to USB-C and a Dell via Display port.
As a guy working with Raspberry Pi and 3D printers a lot in my free time it is SO NICE to have the card reader right up front and easy to access. I also love un/plugging just one cord when I’m on the go.