I'm sure you can get it to work at some lower res/refresh rate than what its designed for. But that monitor is DP 1.4 dual link because it needs more than the 32Gbit one gets out of a single DP 1.4 cable to run at 60Hz. So if your happy with 8K@30Hz and your mac can provide DP 1.4 it might work with a single cable. And from what I know of Mac's your probably out of luck except for the latest M1 models which support TB4 and the higher data rate DPs.

That said, the easiest way to get this working is probably to get one of the TB->PCIe expander chassis and plug in an external GPU and let it drive the display.

Desktop PC's/workstations still have their place, and driving multiple high resolution monitors is one of them.

PS: Been drooling over that monitor for the past couple years as an upgrade to my dell 5K's I picked up when apple released their first standalone 5k monitor and more than a few high end mac users apparently ebay'ed their dell monitors to get the apple version. Their loss, my gain... :) Hey apple, why don't you release a 8K monitor? Lol.

(PS: There are a couple other manufactures putting that panel in monitors (viewsonic for one), so its not just dell, and a bunch of 8K tv's if you want higher resolution).