Yup. That's why the best format for me is the "84 key" or "75%", which is roughly "laptop layout". You get all the Fx keys, arrows, home/end/etc, but no numpad, and it's smaller than the "tenkeyless" format.

I find it much more comfortable for having the mouse closer. For some reason, this format doesn't seem as widespread as the one without the Fx row.