Nature is a complex dynamic system. Yes, it can adapt to new influences without becoming instable.
But needlessly bombarding it with artificial chemicals surely has some kind of threshold over which adaptation mostly fails, equilibria get destroyed and the system becomes indeed instable.
> ... as long as it isn't disrupting ecosystems.
Problem is, who can reliably tell when it'll be too much?
IMO not worth risking "everything" for some added convenience of "ingenious" food packaging.