That really depends on your definition of "fucked-up", but there is a long list of nuclear accidents in the US [0], among the more "fucked-up" ones were attempts to dispose of nearly a ton of left-over fissile material in mere landfills [1] and then ultimately losing track of them.

[0] https://en.wikipedia.org/wiki/Nuclear_reactor_accidents_in_t...

[1] https://thebulletin.org/2014/05/thorium-the-wonder-fuel-that...