Extending off what the other commenter said, consolidation within the medical market is a big reason for the opiod epidemic. It's not something that just came out of nowhere, its directly because a large company intentionally pushed for highly addictive drugs to be given to as many people as possible
It's also a big reason for the fact that americans spend far far more on healthcare than other countries. For reference, the US government spends 28% of your tax on healthcare. The UK government spends 18.8%, which is arounge average among western nations. And ON TOP of that, americans pay huge medical fees and insurance.
Inequality is partly caused by the two above issues, combined with the fact that its really damn hard to make much of a company for yourself when a vastly more powerful company is intentionally suppressing or if you're one of the lucky few buying out all of its competition.
Racism and Sexism are at least partly caused by ineqality, but another big part of it comes from the consolidation in mass media. Shock stories on the national news about the actions of ten or fifteen people can cause and deepen ingrained biases about millions.