But isn't COVID novel in the damage it poses to microvascular systems (importantly brain and lungs), compared to other viruses? E.g., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556303/
My understanding is that this is still different from other viruses.
So if large swaths of a country get that damage from delta vs omicron vs some future weaker variant, that could have very different public health consequences in the coming decades...
Disclaimer: In tech for over a decade, but once upon a time I did an honours degree in biochemistry, so I'm only maybe half-capable of musing my way through some of these papers :)