Sweden did a nationwide study, it didn't end well.[1] Several of the bad variants also originated from countries which did not participate in full lockdown (India, Brazil).
Edit: if Omicron becomes a second 2020, I'd pay close attention to how Sweden reacts, given their recent experiences.
Sweden's numbers are really good all things considered [1]
This defies intuition, we would expect a "no restrictions" policy to result in significantly worse outcomes. Maybe the take away is that a healthier population and a better healthcare system is a more significant factor than restrictions and mandates?
Sweden’s death rate is worse than its neighbours but way better than e.g. Belgium and Britain that did lock down.
It’s also significantly better (x2-x4) than Israel by every excess death measure, where Israel locked down super seriously and vaccinated super quickly.
SA is not known to be the origin of the variant, it is merely the first country that sequenced it. It is definitely a fertile ground for mutations, though.