I have to be vaccinated to go to school, to dorm, to enter or exit countries, to travel for business, to travel for leisure, to work in multiple fields (even technology if you have to enter medical facilities), none of this is new.
It might be a bit weird for a desk job, but have you seen most office buildings? When I did a short stint at Oracle the queues for the lift every day, multiple times a day, were dozens to hundreds of people, every single one was packed during peak hours like morning or lunchtime, and I couldn't go a few months without getting sick. Windows that didn't open, recirculated air.