I don't believe anyone ever has or ever will have dominion over the outcome of their actions within any domain - regardless of power they may otherwise wield. The only certainty in life is uncertainty after all. So, I don't find the presence of uncertainty an acceptable lower bound. Additionally, believing our contemporary body of medical knowledge is complete to the point where we aren't currently making mistakes tantamount to mercury laxatives seems to me, dangerously hubristic.

Being able to make choices unconstrained by experts and authorities who believe your decisions are wrong, is the essence of freedom and the impetus propelling all forward progress. Free Inquiry demands we embrace others' self-determination and latitude in their decisions, respecting the near certain presence of unknown unknowns.

More average people now are reading scientific literature than ever before, which should be cause for rejoicing. Sadly, we seem to be ignoring that opportunity and abandoning all semblance of rational, data-driven science. Rather, we're corrupting Science with Religion, skepticism with faith, breaking into factions mutually recognized as heresies. The data are twisted to fit expectations, not dispassionately observed. We're twisting men of science into priests, models into dogma, literature into liturgy, and inquiry into inquisition. We're not going to notice the unknown unknowns until they've already sunk in their fangs and got a mouth full of buttcheek.