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0 pointsvalarauko4y ago0 comments

> The same will hold true when Pfizer/Moderna "print" updated vaccines

To this point - why haven't they? In the spring/summer there was a lot of talk regarding the ability to quickly switch to a new variant recipe, yet that doesn't seem to have happened. The plan for the boosters still uses the original Wuhan strain.

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4 comments · 1 top-level

angelzen4y ago· 3 in thread

How long should be the clinical trials for updated vaccines? Historically, 'on average, vaccine development can take 10-15 years'. We've rushed the current crop of vaccines 10x. It was an emergency, fingers crossed everything works out fine in the end. Is this the new normal? Are we going to throw long-term safety concerns out the window as a matter of normal procedure? Reminder, there is no reboot button. Perhaps 'move fast and break things' is not the right motto to use in vaccine development.

https://www.gavi.org/vaccineswork/how-covid-19-leading-innov...

chownie4y ago

The parts of vaccine development that we fast forwarded were not the research phases, it was the bureaucracy about funding. Vaccines do not get "long term" testing because the immune system is typically done responding within 5 weeks of inoculation, this is not like drug development.

moistly4y ago

The vaccines are not rushed. They have been in development for ages.

https://www.hopkinsmedicine.org/health/conditions-and-diseas...

angelzen4y ago

The delivery technology has been in development for ages. The payload was tested for about 1 year. IIRC the formulation was done early 2020 in 2 days.

Re your link, it asserts 'MYTH: If I’ve already had COVID-19, I don’t need a vaccine.'. I have serious doubts that is the case, see the OA.

The flu vaccines have been on a yearly basis update schedule. As an organics kind of guy that never sit well with me, but I knew little about vaccines and the flu damage seemed low enough to not matter. It's just an inactivated virus, I'm going to get it either way. These days I wonder how safe the iterated flu shot really is.

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