It seems like the definition from your comment would be "Could we take this labeling system, and define different labels or the labels differently?"
I watched some of the youtube, and in the thought experiment she proposes she take a continuous trait(height) and arbitrarily splits it into two buckets. And talks about how this is kinda silly. But this is something we do all the time, with hypertension, diabetes, disabled, Alzheimer's, the 1%, capitalism, Canadian, etc...
And many of these categories are far more continuous than something like sex and gender which as far as categories go are pretty discrete.
Maybe these things are social constructs, but if they are then we surely must come to the conclusion that almost everything we care about in the world is a social construct.