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0 pointsbriefcomment4y ago0 comments

I think GP is referring to the fact that boosters are being pushed, which implies vaccine immunity is not persistent. It has certainly been pushed since when that study was published.

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3 comments · 1 top-level

hprotagonist4y ago· 2 in thread

we still need the primary antibody count up high, because we’re still in a pandemic, thus the desire for boosters.

in both vaccine induced and survivor induced immune responses, long term immune systems come online to store a memory of the disease so that on future challenge, more of those antibodies will be produced by people fairly rapidly after future exposure, even when your blood stream isn’t full of covid antibodies anymore.

When there are this many cases floating around, though, you can't afford to wait for the spin-up time.

If i'm asking for the same image every 500ms from your webserver, do you want to go to disk every damn time, or are you gonna cache it? Same deal, kinda.

nickthemagicman4y ago

Anitbodies fade after several months.

The booster shots are being touted for every 12 months or so.

Not sure your statement tracks.

hprotagonist4y ago

don't conflate primary antibodies with b-cells.

You and I aren't walking around with bloodstreams full of anti-measles antibodies, despite being vaccinated in infancy: but you can bet that you will be if you encounter a bunch of measles in the wild, in relatively short order.

The question is: are the covid vaccines like tetanus vaccines or like measles vaccines? So far, the evidence points to the latter, but the desire for a booster anyway is driven by the fact that SARS-CoV-2 is a pandemic; neither tetanus nor measles are.

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