A lot of game music was also composed with trackers, including some big titles like the original Unreal and others using its engine such as Deus Ex. But tracker music is all about arranging digital samples on a multi-track timeline, requiring an audio output that can play digitized multi-channel sound in the first place…
Scream Tracker 3 did have an Adlib output mode, and there were a few .s3m files out there that used Adlib FM instruments instead of sampled instruments.