We already have plenty of laws to regulate what you can do within your own property so it doesn't inconvenience your neighbours — burning rubbish out your back garden, playing loud music in the middle of the night, putting up structures that block daylight coming into their property etc. etc.

I think having zoning laws that say hotels aren't allowed in "this area" but they are allowed in "that area" isn't unreasonable. (Most people have no problems with a long-term resident going away for a weekend and letting their house on AirBnB, it's when you turn a property in a residential neighbourhood into a permanent short-term let that's the issue.)

There are very few slippery slopes and too much fear about them.

Property ownership, especially real estate, is limited in many ways. Try depositing asbestos in your condo and see how far you get.